Sobre Haohong Pharmaceutical

Haohong (Qihe) Pharmaceutical Technology Co., Ltd. is located in the High-tech Zone of Qihe County, Shandong Province, adjacent to the Yellow River and within the Jinan Economic Circle, enjoying convenient transportation. The company specializes in the R&D and custom production of innovative active pharmaceutical ingredients (APIs) and pharmaceutical intermediates. It passed the ISO 9001:2015 quality management system certification in 2021, was recognized as a Technology-based Small and Medium-sized Enterprise in 2024, and awarded Innovative Small and Medium-sized Enterprise of Shandong Province in 2025.

Haohong has a high-level R&D team and a full range of analytical testing instruments and methods. At present, its production base in Liaocheng is equipped with 30 sets of 3,000–5,000L reactors, with an annual production capacity of 1,000 tons.

The company focuses on the development of active pharmaceutical ingredients and intermediates for anti-cancer, anti-hepatitis C and anti-diabetic therapies, with an emphasis on high-grade intermediates. Its main products include Bicalutamide, Enzalutamide, Apalutamide, Darolutamide, Abemaciclib, Venetoclax, Macitentan, Empagliflozin, Larotrectinib, Apixaban, Rivaroxaban, Ibrutinib, Ceritinib, Pomalidomide, Lenalidomide, Ivacaftor, Tofacitinib, Cabozantinib, Alectinib, etc.

Our products are exported to overseas markets including the United States, Europe, Japan, India, Bangladesh and other regions. The company currently has dozens of high-grade intermediates available for commercial production, and also provides customers with efficient custom synthesis services ranging from gram scale to hundreds of kilograms.

Adhering to the corporate philosophy of "Pragmatism, Innovation, Integrity", Haohong is committed to serving global customers with full dedication!
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Equipe de classe mundial
Formados em universidades de topo mundiais
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P&D avançado
Desenvolvido internamente
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Foco em inovação
Múltiplas tecnologias inovadoras
CAS:1247927-81-6

CAS:1247927-81-6

Modelo: 4-cyclopropyl-2-fluorobenzoic acid
Parâmetros: CAS:1247927-81-6
Molecular Formula:C10H9FO2
Molecular Weight:180.18

CAS:1207294-92-5

CAS:1207294-92-5

Modelo: 5,7-Di-tert-butyl-3-phenylbenzo[d]oxazol-3-ium tetrafluoroborate
Parâmetros: CAS:1207294-92-5
Molecular Formula:C21H26BF4NO
Molecular Weight:395.25

CAS:42055-15-2

CAS:42055-15-2

Modelo: 3-(METHYLAMINO)-1-PROPANOL
Parâmetros: CAS:42055-15-2
Molecular Formula:C4H11NO
Molecular Weight:89.14
EINECS:677-457-3

CAS:100-76-5

CAS:100-76-5

Modelo: QUINUCLIDINE
Parâmetros: CAS:100-76-5
Molecular Formula:C7H13N
Molecular Weight:111.18
EINECS:202-887-1

CAS:770-69-4

CAS:770-69-4

Modelo: 1-ETHYLADAMANTANE
Parâmetros: CAS:770-69-4
Molecular Formula:C12H20
Molecular Weight:164.29

CAS:99-59-2

CAS:99-59-2

Modelo: 2-Amino-4-nitro anisidine
Parâmetros: CAS:99-59-2
Molecular Formula:C7H8N2O3
Molecular Weight:168.15
EINECS:202-770-5

CAS:5398-27-6

CAS:5398-27-6

Modelo: 2,6-DIIODO-4-NITROANILINE
Parâmetros: CAS:5398-27-6
Molecular Formula:C6H4I2N2O2
Molecular Weight:389.92
EINECS:226-429-5

CAS:949-99-5

CAS:949-99-5

Modelo: 4-Nitro-3-phenyl-L-alanine
Parâmetros: CAS:949-99-5
Molecular Formula:C9H10N2O4
Molecular Weight:210.19
EINECS:213-446-8

CAS:80430-23-5

CAS:80430-23-5

Modelo: methyl 2-[(methylsulphonyl)oxy]-5-nitrobenzoate
Parâmetros: CAS:80430-23-5
Molecular Formula:C9H9NO7S
Molecular Weight:275.24
EINECS:279-464-3

CAS:35320-23-1

CAS:35320-23-1

Modelo: (R)-(-)-2-Amino-1-propanol
Parâmetros: CAS:35320-23-1
Molecular Formula:C3H9NO
Molecular Weight:75.11
EINECS:629-219-5

CAS:3048-01-9

CAS:3048-01-9

Modelo: 2-(TRIFLUOROMETHYL)BENZYLAMINE
Parâmetros: CAS:3048-01-9
Molecular Formula:C8H8F3N
Molecular Weight:175.15
EINECS号221-258-2

CAS:6960-42-5

CAS:6960-42-5

Modelo: 7-Nitroindole
Parâmetros: CAS:6960-42-5
Molecular Formula:C8H6N2O2
Molecular Weight:162.15
EINECS:677-504-8

CAS:13096-62-3

CAS:13096-62-3

Modelo: 2,3,4,6-TETRA-O-BENZYL-D-GLUCONO-1,5-LACTONE
Parâmetros: CAS:13096-62-3
Molecular Formula:C34H34O6
Molecular Weight:538.63

Abemaciclib Intermediate

Abemaciclib Intermediate

Modelo: 4-Bromo-2,6-difluoroaniline 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine 2-Bromo-5-formylpyridine 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Parâmetros: 4-Bromo-2,6-difluoroaniline
CAS: 1868-81-7
Molecular Formula: C₆H₄BrF₂N
Molecular Weight: 207.91
Appearance: White to off-white crystalline solid
Purity: ≥98.0% (HPLC/GC)
Density: 1.768±0.06 g/cm³
Boiling Point: 239.4±35.0 °C
Melting Point: 57–61 °C
Storage: Sealed, dry, keep away from light at 2–8 °C
Application: Abemaciclib pharmaceutical intermediate

5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine
CAS: 398565-53-2
Molecular Formula: C₁₂H₂₀N₄
Molecular Weight: 220.03
Appearance: Off-white to light yellow solid
Purity: ≥98.0% (HPLC)
Boiling Point: 368.5±42.0 °C
Density: 1.124±0.06 g/cm³
Storage: Sealed, low temperature and light protection
Application: Key intermediate for Abemaciclib

2-Bromo-5-formylpyridine
CAS: 100422-52-6
Molecular Formula: C₆H₄BrNO
Molecular Weight: 185.91
Appearance: White to light yellow solid
Purity: ≥98.0% (GC/HPLC)
Melting Point: 78–82 °C
Boiling Point: 286.3±30.0 °C
Storage: Sealed, dry, refrigerated preservation
Application: Heterocyclic intermediate for Abemaciclib synthesis

4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole
CAS: 1356339-86-7
Appearance: White to off-white solid
Purity: ≥98.0% (HPLC)
Storage: Sealed, inert gas protection, 2–8 °C, avoid light
Application: Boronic acid ester intermediate for Abemaciclib

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
CAS: 1356339-85-6
Appearance: White to light beige solid
Purity: ≥98.0% (HPLC)
Storage: Sealed, dry, low temperature and light-proof storage
Application: Core benzimidazole intermediate for Abemaciclib R&D and production

Alectinib Intermediate

Alectinib Intermediate

Modelo: 2-(4-Ethylphenyl)-2-methylpropanoic acid 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
Parâmetros: 2-(4-Ethylphenyl)-2-methylpropanoic acid
CAS No.:1247119-83-0
Molecular Formula:C₁₂H₁₆O₂
Molecular Weight:192.26 g/mol
Appearance:White to off-white solid
Purity:≥98%
Density:1.047±0.06 g/cm³
Boiling Point:302.8±11.0 °C (760 mmHg)
Storage:2-8°C, sealed
Application:Alectinib intermediate


2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid
CAS No.:1256584-73-2
Molecular Formula:C₁₂H₁₅IO₂
Molecular Weight:318.15 g/mol
Appearance:White to off-white solid
Purity:≥98%
Density:1.547±0.06 g/cm³
Boiling Point:369.6±27.0 °C (760 mmHg)
Storage:2-8°C, protect from light
Application:Alectinib intermediate


tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
CAS No.:1256584-75-4
Molecular Formula:C₂₅H₂₇IN₂O₂
Molecular Weight:514.40 g/mol
Appearance:White to light yellow solid
Purity:≥98% (HPLC)
Storage:2-8°C, sealed, protect from light
Application:Alectinib key intermediate

Apalutamide Intermediate

Apalutamide Intermediate

Modelo: 2-Fluoro-4-nitrobenzoic acid N-Methyl-2-fluoro-4-nitrobenzamide N-Methyl-2-fluoro-4-aminobenzamide N-Methyl-2-fluoro-4-bromobenzamide Methyl 4-bromo-2-fluorobenzoate 5-Amino-3-(trifluoromethyl)pyridinecarbonitrile
Parâmetros: 2-Fluoro-4-nitrobenzoic acid
CAS: 403-24-7
Molecular Formula: C₇H₄FNO₄
Molecular Weight: 185.11
Appearance: White to light yellow solid
Melting Point: 170–176 °C
Boiling Point: 352.5±27 °C (predicted)
Density: 1.568±0.06 g/cm³ (predicted)
Purity: ≥98.0%
Storage: Sealed, dry, stored at room temperature

N-Methyl-2-fluoro-4-nitrobenzamide
CAS: 915087-24-0
Molecular Formula: C₈H₇FN₂O₃
Molecular Weight: 198.15
Appearance: Light yellow to yellow solid
Melting Point: Unavailable
Boiling Point: 337.1±32 °C (predicted)
Density: 1.358 g/cm³
Purity: ≥98.0% (HPLC)
Storage: Sealed, dry, stored at room temperature

N-Methyl-2-fluoro-4-aminobenzamide
CAS: 915087-25-1
Molecular Formula: C₈H₉FN₂O
Molecular Weight: 168.17
Appearance: Off-white solid
Melting Point: 160–163 °C
Boiling Point: Approx. 320 °C (estimated)
Density: Unavailable
Purity: ≥98.0% (HPLC)
Storage: Sealed, dry, stored at room temperature

N-Methyl-2-fluoro-4-bromobenzamide
CAS: 749927-69-3
Molecular Formula: C₈H₇BrFNO
Molecular Weight: 232.05
Appearance: White crystalline powder
Melting Point: Unavailable
Boiling Point: 284.8±30 °C
Density: 1.545±0.06 g/cm³
Purity: ≥98.0% (HPLC)
Storage: Sealed, dry, stored at room temperature

Methyl 4-bromo-2-fluorobenzoate
CAS: 179232-29-2
Molecular Formula: C₈H₆BrFO₂
Molecular Weight: 233.03
Appearance: White to off-white solid
Melting Point: 58–62 °C
Boiling Point: 272.7±25 °C
Density: 1.577±0.06 g/cm³
Purity: ≥98.0% (GC)
Storage: Sealed, dry, stored at room temperature


5-Amino-3-(trifluoromethyl)pyridinecarbonitrile
CAS: 573762-62-6
CAS: 573762-62-6
Molecular Formula: C₇H₄F₃N₃
Molecular Weight: 187.12
Appearance: Off-white to yellow solid
Melting Point: Unavailable
Boiling Point: 362.2±42 °C (predicted)
Density: 1.45±0.1 g/cm³ (predicted)
Purity: ≥97%~≥99.0%
Storage: Keep away from light, stored at room temperature under inert atmosphere

Galeria da empresa

Certificações e prêmios

Utility Model Patent
Utility Model Patent
Utility Model Patent
Utility Model Patent
Utility Model Patent
Utility Model Patent
Utility Model Patent
Utility Model Patent
ISO 9001:2015 Quality Management System Certificate
ISO 9001:2015 Quality Management System Certificate

Histórias de sucesso

Top-tier Pharmaceutical Group

Top-tier Pharmaceutical Group

1High reaction yield reduces the production cost of finished pharmaceuticals.
2Low levels of impurities, heavy metals and residual solvents minimize drug safety risks.
3Stable quality across batches improves the consistency of customers’ pharmaceutical production.
4Simplified downstream synthesis processes shorten drug development cycles.
5Accelerates the drug registration process.
Ultra‑high purity with strictly controlled impurities, heavy metals and residual solvents.
Consistent quality batch‑to‑batch, stable crystal form and particle size.
Strict compliance with ICH, GMP and international pharmaceutical standards.
Stable large‑scale production capacity and reliable supply chain.
Customizable R&D support for API synthesis and drug registration.

📍 Localização: US,AE,AU,BD,CA,CN,DE,FR,KR,SA,GB,IN,SG,SE 📦 Quantity: 200

Vídeos da empresa e produtos

Introdução da empresa e tour pela fábrica

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Demonstração do produto - Kestrel K-1

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Showcase de inovação tecnológica

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Depoimentos de clientes e histórias de sucesso

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